Ageing is a natural process we all go through, and as a result we’re faced with the inevitability of wrinkles, fine lines, and loss of skin elasticity. Many clients that visit my London clinic are looking for effective treatments that provide really natural looking results without invasive procedures, but they aren’t sure where to start. 

This is because the beauty industry is extremely hard to navigate. So many different products claim to be the ‘next best thing’ to restore a youthful appearance. But how do you look beyond the hype and find out many of these products and treatments actually work?

The Promise Of Youthful Skin

Traditional anti-aging treatments, like dermal fillers and Botox have proven to be effective in addressing many skincare concerns. Whilst good practitioners aim to achieve the most natural look possible with these treatments, by their very nature they either increase volume or paralyse muscles to achieve desired effects. This isn’t the best option for all clients, leaving them looking for alternative options that provide even more natural, but highly effective results.

Enter polynucleotides. This new and innovative treatment uses the power of DNA for skin rejuvenation, and provides a really natural-looking solution for ageing skin. Dr Selina Clinics is one of the best East London providers for polynucleotides, and I’m seeing an ever-increasing number of requests for this game-changing treatment, for good reason! Book a polynucleotides consultation with me in my London clinic to discuss further

In this guide, I’ll explain how polynucleotides work, the main benefits, and why they’re totally changing the skincare game.

What Are Polynucleotides?

Polynucleotides are long chains of nucleotides: essentially the building blocks of DNA and RNA. In the context of skincare, they’re usually derived from highly-purified salmon or trout DNA. This makes polynucleotides a natural and biocompatible (body-safe) ingredient. 

Polynucleotides treatments work effectively in areas like the tear troughs (under the eyes). This treatment can be chosen vs traditional fillers because it doesn't add volume or have the potential to create a puffy look. 

Instead, polynucleotides work to improve overall skin quality. They act as ‘biostimulants’, which means they can rejuvenate the skin, and repair damage​ caused by free radicals. 

The Science: How Do Polynucleotides Work?

When injected, polynucleotides interact with skin cells at the site of injection. They are proven to do the following:

1. Activate fibroblasts - this improves your skin’s ability to regenerate cells

2. Collagen production -  collagen is necessary to maintain skin elasticity, which in turn reduces the appearance of wrinkles

3. Hydration - they improve the skin’s ability to retain moisture, which gives a more hydrated and plump appearance. They also strengthen the skin’s natural barrier, which means less water loss

What Are The Benefits of Polynucleotides?

1. Natural Results:   

Unlike fillers that add volume, polynucleotides work by enhancing the skin's natural regenerative processes. The result of regular use is naturally smoother, and more refined skin texture.

2. Long-Lasting Effects:

After the initial three treatments, the effects of polynucleotide treatments can last up to six months. Maintenance sessions can then be carried out once every six months. 

3. Versatility:

These treatments can be used on various parts of the body, including the face, neck, hands, and décolletage, offering comprehensive anti-aging benefits. The regenerative properties of polynucleotides also make them really good for repair, so they can be used to reduce the appearance of scars and post inflammatory hyperpigmentation.

How Do Polynucleotide Treatments Compare to Traditional Anti-Aging Methods?

Dermal Fillers vs. Polynucleotides

- Purpose: Dermal fillers primarily add volume to specific areas, while polynucleotides enhance the overall quality of the skin.

- Depth of Injection:  Fillers are injected deeper to provide a volumizing effect, whereas polynucleotides are injected into more superficial layers of the skin.

- Reversibility: Fillers can be dissolved if necessary, but polynucleotide effects are not reversible. This emphasises the importance of visiting a trained medical professional for any cosmetic procedures.

Botox vs. Polynucleotides

- Mechanism: Botox works by temporarily paralysing muscles, which in turn smoothes wrinkles. Polynucleotides do not paralyse muscles, they stimulate cell regeneration.

- Application Areas: Botox is mainly used for dynamic wrinkles (caused by muscle movement), whereas polynucleotides can treat a broader range of ageing signs beyond just wrinkles.

Ideal Candidates for Polynucleotide Treatments

Polynucleotide treatments are suitable for people who are looking to improve skin texture, elasticity, and hydration. They have a natural, subtle, and smoothing effect. They are especially beneficial for:

- Early signs of ageing, such as fine lines and early wrinkles.

- Skin that appears dull

- Sensitivity to other cosmetic treatments, or a preference to have more natural results

The Treatment Process

1. Consultation:

A thorough consultation with a qualified medical professional is essential to determine suitability, and to get a personalised treatment plan.

2. Injection Procedure:

The polynucleotide solution is injected into the targeted areas using fine needles. The procedure is relatively quick, typically taking 30-60 minutes, including numbing time with a topical numbing  cream. 

3. Post-Treatment Care:

Patients are advised to avoid strenuous activities, excessive sun exposure, and certain skincare products for a few days post-treatment.

Side Effects and Precautions

Polynucleotides are generally safe, but be aware of:

1. Mild Irritation: Some people may experience temporary redness and/or small bumps at the injection site. This irritation may last 3-5 days.

2. Allergic Reaction: Although very rare, some may be allergic to fish derived polynucleotides.

Polynucleotides in the Future

As research continues, we’ll likely see the use of polynucleotides rapidly increase in:

1. Combination Products: Scientists are looking into how polynucleotides can be combined with other actives for better results.

2. Targeted Delivery: New technologies may allow for more targeted delivery of polynucleotides to areas of concern.

3. Personalised Skincare: With genetic testing advancing we may see polynucleotide treatments tailored to your DNA.

Conclusion: Polynucleotides for Glowing Skin

Polynucleotides are a scientifically proven solution for a number of skin concerns, because they enhance the skin’s own regenerative properties. But as with any cosmetic treatment, it’s always important to remember that polynucleotides are not a magic pill. Whilst they have the potential to smooth and plump your skin, optimum results will only be achieved when combined with a strong skincare regime, a healthy diet, proper hydration, and sun protection.

If you’re interested in discussing whether polynucleotides are right for you, book a consultation with me at Dr Selina Clinics in South Woodford, London. I’ve seen fantastic results with my clients to date.